Tadalafil is a generic prescription drug that is used to treat several conditions, namely erectile dysfunction (impotence), as well as enlarged prostate (benign prostatic hyperplasia or BPH) and high blood pressure in the lungs (pulmonary arterial hypertension). Tadalafil (like its brand-name counterparts, Cialis® and Adcirca®) belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. These medicines prevent the enzyme PDE5 from working too quickly. The penis is one of the body parts where this enzyme works.
One dose of Tadalafil taken as needed for sexual activity can remain effective for up to 36 hours, however peak concentration of Tadalafil in the bloodstream usually occurs between 30 minutes and 6 hours with a median time of 2 hours. Since tadalafil’s effectiveness lasts for a long time, it can be taken well in advance to allow for more spontaneous sexual activity over the course of a day or night.
Tadalafil dosing depends on whether or not it is taken daily or as-needed. Once-a-day tadalafil builds up in your system to 1.6-times the daily dose, and so the 5 mg daily treatment offered through hims is similar to taking 8 mg of tadalafil before sex. Tadalafil taken as needed for sexual activity is usually used at higher doses because it does not have time to build up in your system. Typical starting doses of as-needed Tadalafil are 10 or 20 mg, depending on your specific health conditions and age.
Tadalafil is the affordable, generic version of brand-name Cialis. Cialis was originally created and is produced by the pharmaceutical company Eli Lilly, and generic tadalafil became available in 2018 after the patent protection ended. Both brand-name Cialis and tadalafil have been shown to be safe and provide the same treatment effects for erectile dysfunction, but tadalafil is available for a fraction of the price of Cialis.
Common side effects of tadalafil include headaches, indigestion, heartburn, back pain, muscle aches, facial flushing, nasal congestion, cold symptoms, dizziness, vision changes and blood pressure changes. If any of these side effects bother you or don’t go away, contact your healthcare provider. Serious side effects are rare, but may include a dangerous drop in blood pressure, sudden vision loss, hearing loss and priapism (an erection lasting four hours or longer). If you experience any of these serious side effects, get medical help immediately.